Amazingly fascinating field. I have learned a (very) small amount about this from Dr. David Sinclair's book Lifespan

I read Sinclair's new book Lifespan and saw Patrick in a podcast. I got really excited and installed the Habinator app, because it's all about the lifestyle and habits until we get a breakthrough how to fix our bodies using pills or whatever.

This truly fascinates me... it's the potential for immense extension of human life that no one's talking about. If you're interested in this topic, I highly recommend the book Lifespan by Dr. David Sinclair.

If you're interested in changes to aging and the growing science behind it, I can't recommend Lifespan by David Sinclair highly enough.

Not to trout a cliche around since plenty of HN has heard of this already, but David Sinclair’s book Lifespan talks about caloric reduction. Nothing crazy, skipping a meal here and there.

Follow this advice and you'll increase your chances of growing older increases quite a lot, and you'll stay healthier in your older years as well.

There is only so far these things can take us though. A lot of (but still too little) research is being done on slowing down or maybe even reversing aging, which could increase our lifespan to 150 (or maybe even longer). Not only would we live longer, but we would stay healthier for longer as well.

If you're interested, make sure to check out the longevity subreddit[0], some longevity discords[1][2]. Also make sure to read Lifespan by Dr. David Sinclair[3] and/or Ageless by Dr.Andrew Steele[4]

Some other things to keep an eye on:

  - Blood pressure
  - Resting heart rate
  - Brush teeth twice a day
  - Reduce meat
  - Don't smoke
  - Reduce alcohol
  - Avoid stress
  - Your mental health

--

0. https://www.reddit.com/r/longevity

1. https://discord.gg/HwTX7gR

2. https://discord.gg/ftSbffu

3. https://www.amazon.com/Lifespan-Why-Age-Dont-Have/dp/0008380...

4. https://andrewsteele.co.uk/ageless/ (not yet released in the US)

X. Longevity knowledgebase: https://brain.forever-healthy.org/display/EN/Longevity+Strat...

Lifespan: Why We Age-and Why We Don't Have To - David Sinclair [1]

[1] https://www.amazon.com/Lifespan-Why-Age-Dont-Have-ebook/dp/B...

Prior to the pandemic I went to the gym 3-4 days/week, alternating between HIIT on a bike and an endurance workout on an elliptical. I knew I would need to find an alternative since gyms were no longer safe, but due to space restrictions knew I couldn't get the same equipment I use at the gym.

I set up alerts on OfferUp and Craigslist for a Nordictrack ski machine. Got one back in April for $100 and have used it 6-7 days a week since. It fits in a relatively small space, doesn't require power, and is 100% user serviceable. I have it along the wall in the garage, and can fold it up if need be. I only do my "long" workout on it, but am planning to try my first HIIT workout on it tonight!

I also have started doing the kettlebell routine from the book "Simple & Sinister" using a 16 kg kettlebell I bought ages ago and never used. The /r/kettlebell community is very, very helpful. I was, to be brutally honest, intimidated to start this; I was sure that I would somehow do the exercises wrong and wind up hurting myself. However, nothing bad's happened and I do feel better/stronger.

Finally, I've done more reading on health/longevity (most recently the book Lifespan by Sinclair) and have modified my eating habits a bit.

The pandemic sucks, but being forced to come to grips with months of my life being heavily restricted served as motivation to live healthier so I can make more use of the time that's left once (a) a vaccine come around or (b) I figure out how to immigrate to New Zealand and live a normal life :-)

For reference, the generally accepted standard for determining age from blood is the Horvath clock [1]. It seems to be accurate and only uses a penalized regression. Keep in mind this represents what your age is in reference to a "healthy" person. For example, a 50-year-old who smokes may have the equivalent practical age of a 60-year-old who doesn't. The Horvath clock is useful for evaluating lifestyle changes and your overall healthspan.

If people want to learn more about how DNA methylation relates to aging, I recommend reading Lifespan by David Sinclair.

[1] https://www.semanticscholar.org/paper/DNA-methylation-aging-...

There is a real possibility that in the next few decades some of these therapies might work.

The book Lifespan by Dr David Sinclair is really interesting. Sinclair is a professor at Harvard. He's highly optimistic that something will come of the various ideas looking at slowing aging.

https://www.amazon.com/Lifespan-Why-Age_and-Dont-Have/dp/150...